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The referenced work presents two alternative modeling approaches for muscle spasm response to vismodegib. This is a fit of the provided proportional odds model to the 50 participant mock data.

Usage

vismo_pomod

Format

xp_xtras

An xp_xtras object.

Source

Derived from sup-0009 and sup-0010 from the reference.

References

Lu, T., Yang, Y., Jin, J.Y. and Kågedal, M. (2020), Analysis of Longitudinal-Ordered Categorical Data for Muscle Spasm Adverse Event of Vismodegib: Comparison Between Different Pharmacometric Models. CPT Pharmacometrics Syst. Pharmacol., 9: 96-105. doi:10.1002/psp4.12487

Examples

# To establish as a complete categorical DV example:
vismo_pomod <- vismo_pomod  %>%
  set_var_types(.problem=1, catdv=DV, dvprobs=matches("^P\\d+$")) %>%
  set_dv_probs(.problem=1, 0~P0,1~P1,ge(2)~P23)